Our laboratory is defining molecular mechanisms that underly the development of an egg from its precursor cell, the oocyte. To address these questions, we are working at the interface between cell biology and development, with the sea star Patiria miniata and its relatives. Sea stars produce millions of oocytes throughout their lives, and are amenable to many experimental tools. As relatives to the animal group that includes vertebrates like ourselves, the sea star can teach us important lessons relevant for human reproductive health, disease, and aging.

photo credit: Conor Gearin